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Undergrads - Summer 2012 (6)
This PubGroup includes all journal articles discussed at the Journal Club of undergraduate researchers during the Summer of 2012.
A new look at bacteriophage lambda genetic networks.
journal of bacteriology
Court DL, Oppenheim AB, Adhya SL., 2007
This article describes the complex lambda integration system, and is useful in contrasting it against the mycobacteriophages' integration systems. (To be discussed 6/26/12, Undergraduate Journal Club, Summer 2012)
Enoch Tse
June 26, 2012
Comparative genomic analysis of 60 Mycobacteriophage genomes: genome clustering, gene acquisition, and gene size.
Journal of molecular biology
Hatfull GF et al, 2010
Colloquially known as the "60-phage paper," this paper doubled the previously published number of phages, and introduced several new clusters and pieces of evidence for mosaicism. (To be discussed 6/19/2012, Undergraduate Journal Club, Summer 2012)
Enoch Tse
June 19, 2012
Rewritable digital data storage in live cells via engineered control of recombination directionality.
Proceedings of the National Academy of Sciences of the United States of America
Bonnet J, Subsoontorn P, Endy D., 2012
Recommended in the Hatfull Lab meeting, this paper utilizes data generated from Dr. Hatfull and Dr. Ghosh regarding the bxb1 integrase. (To be discussed 6/12/2012, Undergraduate Journal Club, Summer 2012)
Dr. Graham Hatfull
May 31, 2012
Cluster K mycobacteriophages: insights into the evolutionary origins of mycobacteriophage TM4
PLoS One
Pope WH, Ferreira CM, Jacobs-Sera D, et al, 2011
This paper closely investigates Cluster K phages, including looking at immunity and introducing the discovery of Start-Associated-Sequences (SAS) and Extended Start Associated Sequences (ESAS). (To be discussed 6/7/2012, HHMI Journal Club, Summer 2012)
Enoch Tse
June 7, 2012
Prokaryotes: the unseen majority
Proc Natl Acad Sci U S A
W. Whitman, D. Coleman, W. Wiebe, 1998
This paper establishes the estimated number of bacterial cells on the planet, which in turns provides a foundation for the estimation of the number of bacteriophages associated. (Discussed 5/29/2012, Undergraduate Journal Club, Summer 2012)
Enoch Tse
May 29, 2012
Expanding the diversity of mycobacteriophages: Insights into genome architecture and evolution
PLoSOne
Pope WH et al, 2011
This is one of the most recent papers that provides comparative genomic analysis of 18 newly isolated and sequenced mycobacteriophages. It offers valuable insights into the genomic diversity of phages. It is a great first paper to read for all new lab members.
Dr. Graham Hatfull
June 7, 2012