What is DOGEMS?
Deconvolution Of Genomes after En Masse Sequencing, or DOGEMS (DAH-jums), is an approach to sequencing phages where individually isolated phage DNA samples are deliberately mixed before preparing libraries. The main reasons to do so are to reduce library …
Gene Content Similarity and Dissimilarity
Last year, one of the grad students in the Hatfull lab, Travis Mavrich, was the lead author on a paper in Nature Microbiology that explored the extent to which horizontal gene transfer and mosaicism …
I've gotten a few questions recently about doing phage genome sequencing on Illumina sequencers, and we ourselves have been pumping genomes through our Illumina MiSeq and loving it. But I wanted to issue a word of caution to anyone considering …